NMDA Modulation in Pain: Underappreciated or Broken Promises?
The N-methyl-D-aspartate (NMDA) receptor has played a role in pain management for years. However, evidence to support use of NMDA antagonists can be hard to interpret and is often contradicting. This presentation will focus on the physiology of the NMDA receptor, its role in windup/central sensitization, and the existing evidence for use of NMDA antagonists, including amantadine, ketamine, memantine, and dextromethorphan in pain management.
Learning Objectives
- Identify the role of NMDA in central sensitization
- Describe the role of NMDA in the physiology of pain
- Compare clinical evidence between the NMDA antagonists
Available Credit
- 1.00 AANP
- 1.00 ACCME (All Other)
- 1.00 ACCME (MD/DO Only)
- 1.00 ACPE Pharmacy
- 1.00 ANCC
- 1.00 APA